Vitamin B12 and Eczema
April 18, 2009 Written by JP
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One of the more difficult things for a parent to endure is seeing a child suffer from a chronic condition. It’s especially hard if the condition affects the skin, which often attracts unwanted attention and can cause psychological distress as well.
Eczema is one of the most common skin disorders in young children and some adults. It may affect as many as 20% of children in the USA. Eczema is defined by an irritation and swelling of the skin that frequently involves extreme dryness and itchiness.
There are conventional treatments available for eczema, but they carry the risk of serious side effects. One reason is the need for long term term treatment, as eczema is incurable. In addition, the condition frequently covers large areas of skin, thereby necessitating large amounts of medication.

The April 2009 issue of the Journal of Alternative and Complementary Medicine provides a viable and safe alternative to the potentially dangerous drugs that are in use today. A trial was set up to investigate the efficacy of a Vitamin B12 cream in the treatment of children with atopic dermatitis (eczema).
Twenty-one patients with ages ranging from 6 months to 18 years enrolled in this 4 week trial. Each volunteer applied either a Vitamin B12 cream or a placebo cream to symptomatic areas on opposite sides of their bodies. For instance, the B12 cream was only applied to the right side and the placebo was exclusively used to treat the left side. This allowed for a comparison model for the two treatments.
At the end of weeks 2 and 4, an investigator performed skin checks using a “standardized scoring system”. The findings were expressed in this manner, “Skin treated with topical vitamin B(12) improved significantly more than placebo treated skin at 2 and 4 weeks. Topical vitamin B(12) should be considered as a treatment option in children with eczema.”
In May of 2004 another study was presented in the British Journal of Dermatology. It was a larger experiment that focused on adults with eczema. In it, 49 participants applied a Vitamin B12 cream or a placebo cream to opposite sides of their bodies. They did so for a total of 8 weeks.
Those applying the B12 cream noted a 55% improvement in their eczema symptoms. When the volunteers were asked to describe the effects of both creams, in most cases they evaluated the B12 cream as being “good” and “very good”. The placebo cream was generally described as being of “moderate” use or providing “poor” results. Based on symptom regression and patient feedback, the researchers concluded that, “These results document a significant superiority of vitamin B(12) cream in comparison with placebo with regard to the reduction of the extent and severity of atopic dermatitis. Furthermore, the treatment was very well tolerated and involved only very low safety risks for the patients.”
It appears that other severe and chronic skin maladies are receptive to topical B12 treatment as well. In 2001, a study was described in the journal Dermatology. This time the focus of the scientific inquiry was the management of chronic plaque psoriasis with an avocado oil and B12 cream.
Instead of a placebo, a Vitamin D based medication was compared to the B12 cream. Vitamin D analogs have been traditionally used with some success in managing the symptoms of psoriasis. Exposure to natural sunlight, which the skin uses to produce Vitamin D, is also known to benefit some psoriasis sufferers.
Over the course of 12 weeks, 13 female and male volunteers were provided both treatments. Once again, the investigators utilized a “right/left side comparison technique” to determine the respective effects of each type of treatment.
The Vitamin D based medication brought about quicker results, but they tended to fade after 8 weeks. The avocado oil/B12 cream’s positive effects remained constant throughout the 12 week period, and both the patients and the investigators found that it was better tolerated. Because of the more consistent therapeutic effect and greater tolerability, the B12 topical was considered better suited for the “long-term treatment of psoriasis.”

It’s great to know that there are safe and natural topical treatments that can help reduce the symptoms of eczema and psoriasis. But it’s important to remember that what you put into your body can also have a profound effect on the condition of your skin. In particular, food allergies and sensitivities, an imbalance of the good and bad bacteria in the digestive system and a lack of healthy fats in your diet can all contribute to the worsening of skin conditions such as eczema. If we only approach skin disorders from the outside in, we’re missing a big part of the picture.
Be well!
JP
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Tags: Eczema, Psoriasis, Skin Care
Posted in Children's Health

October 6th, 2010 at 10:13 pm
can we buy vitamin B12 cream in local pharmacies?
what are the brands?
October 6th, 2010 at 10:20 pm
MC,
Vitamin B12 creams can be made by compounding pharmacies.
Be well!
JP
October 6th, 2010 at 10:33 pm
Hi JC
Quick reply thanks!
You’d think I can make my own B12 cream by compounding the B12 tablets into my own choice of moisturizing cream?
October 6th, 2010 at 10:51 pm
MC,
I’m afraid it’s not so simple. B12 capsules and tablets contain binding agents and fillers. It would probably be best to buy a compounded cream or lotion that can be formulated to contain an appropriate percentage of B12. It’ll be more expensive to be sure. But hopefully it’ll also be worth it.
Be well!
JP
January 22nd, 2011 at 7:35 am
I have a b12 serum (drops). Can I add some to any of my body creams and it will be effective in treating the eczema? If so how much do i add to how much cream?
January 22nd, 2011 at 7:40 am
Would adding b12 in liquid form to any body cream be effective in treating my skin problem? If so, how much b12 to how much cream?
January 22nd, 2011 at 1:30 pm
Helen,
It probably depends on what other (inactive) ingredients are also contained in the B12 liquid. Such products often contain added colors, flavors and sweeteners.
The amount of B12 used in the study was minute .07%.
http://bastyrcenter.org/content/view/409/
Be well!
JP