Comments on: Metformin Updates http://www.healthyfellow.com/442/metformin-updates/ Your Natural Health Critic Thu, 09 Feb 2012 18:34:21 +0000 hourly 1 http://wordpress.org/?v=3.0.4 By: JP http://www.healthyfellow.com/442/metformin-updates/comment-page-1/#comment-6009 JP Fri, 21 Jan 2011 18:37:47 +0000 http://www.healthyfellow.com/?p=442#comment-6009 Hussain, That appears to be the primary mechanism: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017330/?tool=pubmed http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.2010.05679.x/abstract Be well! JP Hussain,

That appears to be the primary mechanism:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017330/?tool=pubmed

http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.2010.05679.x/abstract

Be well!

JP

]]> By: hussain http://www.healthyfellow.com/442/metformin-updates/comment-page-1/#comment-5997 hussain Wed, 19 Jan 2011 20:20:56 +0000 http://www.healthyfellow.com/?p=442#comment-5997 thank you for this blog. i want to ask please, is metformin is usefull in polycystic ovary syndrome only by increasing insulin sensitization or there are another PROVED mechanisms? thank you for this blog. i want to ask please, is metformin is usefull in polycystic ovary syndrome only by increasing insulin sensitization or there are another PROVED mechanisms?

]]> By: JP http://www.healthyfellow.com/442/metformin-updates/comment-page-1/#comment-2150 JP Thu, 07 Jan 2010 19:17:47 +0000 http://www.healthyfellow.com/?p=442#comment-2150 You're very welcome, DE! :) Be well! JP You’re very welcome, DE! :)

Be well!

JP

]]> By: DE http://www.healthyfellow.com/442/metformin-updates/comment-page-1/#comment-2149 DE Thu, 07 Jan 2010 18:48:14 +0000 http://www.healthyfellow.com/?p=442#comment-2149 Thank you for this informative blog. I may need to ask my doctor about this treament! Thank you for this informative blog. I may need to ask my doctor about this treament!

]]> By: JP http://www.healthyfellow.com/442/metformin-updates/comment-page-1/#comment-2142 JP Thu, 07 Jan 2010 02:42:35 +0000 http://www.healthyfellow.com/?p=442#comment-2142 Happy New Year, Iggy! :) That's an interesting find! Thank you for bringing to my/our attention. I found this portion of the study abstract interesting too: "Although insulin and metformin display opposing effects on Abeta generation, in combined use, metformin enhances insulin's effect in reducing Abeta levels." http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656178/?tool=pubmed I think this is all based primarily on one study - though it seems to be a pretty intriguing one. I'll keep an eye out to see if other research supports or refutes this finding. Be well! JP Happy New Year, Iggy! :)

That’s an interesting find! Thank you for bringing to my/our attention.

I found this portion of the study abstract interesting too:

“Although insulin and metformin display opposing effects on Abeta generation, in combined use, metformin enhances insulin’s effect in reducing Abeta levels.”

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656178/?tool=pubmed

I think this is all based primarily on one study – though it seems to be a pretty intriguing one. I’ll keep an eye out to see if other research supports or refutes this finding.

Be well!

JP

]]> By: Iggy Dalrymple http://www.healthyfellow.com/442/metformin-updates/comment-page-1/#comment-2141 Iggy Dalrymple Thu, 07 Jan 2010 02:19:06 +0000 http://www.healthyfellow.com/?p=442#comment-2141 There is another red flag concerning metformin. There is some evidence that that it increases amyloid plaque associated with Alzheimer's Disease....however some scientists question if amyloid plaque is a cause of AD. I've taken metformin for years and continue to do so. http://www.medscape.com/viewarticle/589647 There is another red flag concerning metformin. There is some evidence that that it increases amyloid plaque associated with Alzheimer’s Disease….however some scientists question if amyloid plaque is a cause of AD.

I’ve taken metformin for years and continue to do so.
http://www.medscape.com/viewarticle/589647

]]> By: JP http://www.healthyfellow.com/442/metformin-updates/comment-page-1/#comment-2137 JP Wed, 06 Jan 2010 16:59:25 +0000 http://www.healthyfellow.com/?p=442#comment-2137 Sai, I couldn't agree more with your points. :) Supplementing with folic acid, B6 and B12 is probably a wise move when using Metformin. Another option might be to take a higher potency multivitamin or a B-complex supplement. By doing so, it virtually eliminates the risk of deficiency and harmful elevations in homocysteine. Blood tests can confirm both of these assertions. I hope you have a wonderful day too, Sai! :) Be well! JP Sai,

I couldn’t agree more with your points. :) Supplementing with folic acid, B6 and B12 is probably a wise move when using Metformin. Another option might be to take a higher potency multivitamin or a B-complex supplement. By doing so, it virtually eliminates the risk of deficiency and harmful elevations in homocysteine. Blood tests can confirm both of these assertions.

I hope you have a wonderful day too, Sai! :)

Be well!

JP

]]> By: Sai http://www.healthyfellow.com/442/metformin-updates/comment-page-1/#comment-2134 Sai Wed, 06 Jan 2010 13:43:54 +0000 http://www.healthyfellow.com/?p=442#comment-2134 Good Day JP! Thanks much for a very useful article. While Metformin is a very good drug it does deplete the B12 levels (partucularly vegetarians) so one should be on the look out for that. Another interesting point is, while the maximum dosage allowed in the US is 2500 mg, it is only 1700 mg in India and the UK. My personal point is if someone has elevated blood sugar, then Metformin should be the first line of treatment along with the other changes in Diet and lifestyle that would reverse their condition. But more often some anti-diabetic medications are prescribed as i have seen in so many instances. Even in my own case there was reduction in ldl and trigyclerides when put on metformin (back to normal). You concluding statement about Dr. Bernie Siegel was very true and important too. Have a pleasant day :-) Best Regards Sai. Good Day JP!

Thanks much for a very useful article. While Metformin is a very good drug it does deplete the B12 levels (partucularly vegetarians) so one should be on the look out for that. Another interesting point is, while the maximum dosage allowed in the US is 2500 mg, it is only 1700 mg in India and the UK. My personal point is if someone has elevated blood sugar, then Metformin should be the first line of treatment along with the other changes in Diet and lifestyle that would reverse their condition. But more often some anti-diabetic medications are prescribed as i have seen in so many instances. Even in my own case there was reduction in ldl and trigyclerides when put on metformin (back to normal). You concluding statement about Dr. Bernie Siegel was very true and important too. Have a pleasant day :-)

Best Regards

Sai.

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