Chlorella and Spirulina
January 6, 2010 Written by JP
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In the world of high fashion models there are certain physical traits that you expect to find in the men and women strutting down the catwalk. But every once in a while an unlikely superstar emerges. These individuals generally don’t possess the typical characteristics found in other “supermodels”. They may be heavier, shorter or just downright “unique” in appearance. A similar phenomenon is found in the field of naturopathic medicine. There are plenty of remedies derived from beautiful sources such as echinacea flowers, lavender buds and milk thistle. However other popular supplements are extracted from decidedly unattractive reservoirs.

In the eyes of many people, algae such as Chlorella and Spirulina are nothing more than common pond scum. Alternative medicine buffs and research scientists vehemently disagree with that point of view. Both perspectives have a basis in reality. Certain varieties of algae can, in fact, be toxic and virtually all algae have an unpleasant aroma and taste. Naturally, these attributes lend themselves to giving algae a bad reputation. But under a microscope or in the context of medical studies, these very same outcasts are often found to have very promising health promoting features.(1,2,3)
Here’s a bullet point overview of some of the most recent data relating to both of these blue-green supermodels:
- Chlorella and Pregnancy - A group of 70 women with pregnancy anemia and pregnancy induced hypertension (PIH) were given either 6 grams/daily of Chlorella or a placebo from the 12th week of gestation until delivery. Those receiving the Chlorella supplements demonstrated improvements in anemia in their second and third trimesters - as measured by hemoglobin levels. Two key signs of pregnancy induced hypertension (edema and proteinuria) also declined in the Chlorella users during the third trimester. The Japanese scientists conducting the trial noted that Chlorella contains organic sources of folic acid, iron and Vitamin B12 which probably contributed to some of the health benefits exhibited in this study. (4)
- Chlorella and Smokers - A study published in the August 2009 edition of the journal Nutrition examined the effects of Chlorella supplementation in a group of male smokers. A group of participants with ages ranging from 20 to 65 were asked to take 6.3 grams of Chlorella vulgaris or a placebo over the course of 6 weeks. Blood samples were taken pre and post trial. The results of the testing revealed that the Chlorella users showed increased levels of select antioxidants such as Vitamins C (44% higher) and Vitamin E (16% higher). There were also indications of greater systemic antioxidant enzymes (erythrocyte catalase and superoxide dismutase) and a reduction in DNA damage resulting from tobacco use. The researchers concluded that “Chlorella is an important whole-food supplement that should be included as a key component of a healthy diet”. (5)
- Chlorella and Animal Studies - Several recent animal trials also shed light on potential future applications for Chlorella. An October 2009 study in the journal Neuroscience Letters describes how Chlorella supplementation can decrease age-related oxidative stress and prevent cognitive decline in older mice. That same month, another trial in the Journal of Medicinal Food reports that adding Chlorella to an unhealthy diet “may prevent insulin resistance” in diabetes-prone rats. In addition, a Taiwanese study determined that Chlorella is as effective as milk thistle in protecting the liver of lab rats against chemically induced damage. This is noteworthy because milk thistle is considered the number one natural remedy for supporting liver health. (6,7,8)
- Spirulina and Athletic Performance - Adding 6 grams daily of Spirulina to the diets of “moderately trained males” for 4 weeks was shown to improve exercise performance and stamina, increase fat burning and systemic antioxidant levels (glutathione/GSH) and reduce exercise induced oxidative stress (lipid peroxidation). (9)
- Spirulina + Chlorella and Heavy Metals - A new experiment conducted at the Department of Pharmacology at the Mymensingh Medical College in Bangladesh discovered that Spirulina extracts can effectively remove arsenic from the livers of mice suffering from arsenic poisoning (arsenicosis). In September 2009, a group of Japanese researchers also reported that Chlorella could “contribute to the prevention of gastrointestinal absorption of lead and the promotion of the excretion of lead” in mice. In many parts of the world, heavy metal exposure is a leading cause of developmental disorders and illness. Medicinal algae may be a safe and viable strategy to mitigate such a risk in regions where arsenic or lead exposure is common. (10,11)
- Spirulina and Diabetes - 30 days worth of Spirulina supplementation provoked positive changes in diabetic rats according to an Indian study from Pondicherry University in Kalapet. Improvements in blood glucose, body weight, insulin and pancreatic health were noted. Yet another Indian trial determined that combining Spirulina with a common anti-diabetic medication (Rosiglitazone or Avandia) could reduce the risk of drug related bone loss in a group of insulin resistant rats. The authors theorized that the calcium and phosphorous in Spirulina may account for the bone strengthening effect noted. I would personally add that Vitamin K and Vitamin K2 may also be at work here. In addition, improvements in “fasting serum glucose, HDL, LDL and triglycerides” were found in the rats receiving the Spirulina/drug combination. (12,13)

While searching through the scientific literature I wasn’t surprised to find numerous studies emanating from Asian countries such as China, Japan and Korea. But what I found particularly interesting was the rather impressive number of algae experiments conducted in India. I simply wasn’t aware of the commercial or traditional use of therapeutic algae in that country. Apparently, I wasn’t the only one who was taken aback by this news. A scientific review of traditional Indian plants in the September 2009 edition of the Journal of Ethnopharmacology includes Chlorella vulgaris in it’s evaluation of this topic. The authors describe Chlorella and 12 plant species as “reported for the first time for the treatment of inflammation related diseases” in the Indian healing tradition. (14)
Future prospects also look particularly bright for medicinal algae. An eye drop consisting of an extract of Spirulina platensis is currently being evaluated for corneal diseases of the eye such as macular degeneration. Preliminary evidence suggests that this natural eye drop may one day offer a more affordable and safer option to currently available drugs including Avastin and Lucentis. (15)
The human studies I’ve referenced today have utilized encapsulated or tableted forms of Chlorella and Spirulina. Both algae have a somewhat aquatic flavor and odor. Therefore, most people prefer swallowing a handful of algae pills rather than sprinkling it into their morning cereal or yogurt. However, it is often possible to mask the taste quite well in a protein shake or smoothie. At the moment, I’m taking a “green food” supplement that comes in a capsule form. In the past I have also used a mixed greens formula that provided both Chlorella and Spirulina in a delicious powder form - no joke! This is one type of supplement that can largely be influenced by your taste. If you have a sensitive palate, I would suggest opting for capsules, tablets or naturally flavored powdered forms. Be sure to choose a form that suits your needs. If you can’t stand the taste, it’s unlikely that you’ll take it consistently.
Be well!
JP
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Tags: Chlorella, Diabetes, Spirulina
Posted in Nutritional Supplements


January 7th, 2010 at 3:54 am
Morning JP,
nice topic. on my desk lie a few product samples of chlorella and spirulina. i read that some dentists use those to detox after a amalgam filling removal (toghether with cilantro and wild ramsons or wild garlic). the producer is greenvalley (thats the brand, they produce in japan, india and usa all organic). i read on a few sites that algae can also remove radioactive minerals off the body like uranium from water and therefore clean the kidneys and the liver, cleanse from mercury and lead and so on.
hubby and i lived 3 years in bavaria and drinking water there is often contaminated with uranium - very high levels. for bottlet water theres a limit of 2 mcg/l but the drinking water out of the water tap contains there in some places more than 18-32 mcg/l! bad for babys! i didn’t know that for a long time
so i think im contaminated
the only bad thing about algae is that their vitamin b12 is an analog to the form that our body can use. so if taken to much from algae our vitamin b12 receptors are blocked with a for us non working vitamin b12. thats a little bit a problem. read about vegetarian ladies which had supplemented during pregnancy with algae and their offsprings are handicapped because of vitamin b12 deficiency. this point should be considered.
however beyond that is a good way to alkalize blood and detox and clean body (my opinion :-)) so for now i have to overcome the taste and try my samples
bon appetite!
Nina K.
January 7th, 2010 at 4:09 am
Dear JP,
You have made all these complex information so easy to understand for the reader. Your work and rasearch are wonderful. Thanks for created a wonderful health resource center.
January 7th, 2010 at 12:14 pm
Good day, Nina!
I’ve also been in contact with some alt-med doctors who include chlorella to manage established or suspected heavy metal exposure (mercury is often cited).
I’m sorry to hear of the contaminated water in your home land. It seems none of us can entirely escape one type of health hazard or another. The best we can do is avoid what we can and protect against any unknown insults via diet, lifestyle and the judicious use of supplements. Apart from that, we can keep our fingers crossed or pray!
Your point about Vitamin B12 is a good one. In fact, I wouldn’t take algae along with most other supplements. Taking Chlorella and Spirulina on an empty stomach may be best for this reason (B12) and others such as it’s ability to bind to metals.
I hope the taste of your sample supplements is better than you imagine! Good luck!
Be well!
JP
January 7th, 2010 at 12:15 pm
Thank you, Morello!
Be well!
JP
January 7th, 2010 at 12:59 pm
Hi JP! Happy new year! A great article on the wonders of pond scum! I am also hoping that algae may prove to be valuable as an energy source one day, but I guess that is another topic
As always, I must stress the importance of taking a QUALITY greens supplement. Beware the powered greens “miracle” packets at the grocery checkout! They may taste delicious but most of the time contain very little nutrients that can be readily absorbed by the body.
Best wishes, Bill
January 7th, 2010 at 1:16 pm
Happy New Year, Bill!
I’m not sure if algae will ever come into it’s own with regard to global energy but I think it can play a role presently in individual energy!
We agree that quality is important when considering “greens” or any supplement. It’s not just what you put in your body but also what impurities you keep out of it. Low quality algae supplements that lack purity and that include lots of fillers and questionable ingredients should definitely be avoided. Thank you for pointing out that important factor!
Be well!
JP
January 7th, 2010 at 9:08 pm
Hello JP!
I am having the amazing grass superfood which has both these algae as a bed-time drink as i see your well written and researched article.I also wanted to ask your thoughts on carb blockers and their effect on blood sugar! Since having this superfood my uric acid levels (which is always in 8 or 9 range has come to 7.8 and getting better. Thanks again for all your useful and informative postings.
Best Regards
Sai
January 8th, 2010 at 12:59 am
Good day, Sai!
I’m thrilled to hear about the decline in your uric acid levels.
re: starch blockers
Do you eat many carbs in your daily diet? The reason I ask is because alpha amylase inhibitors (such as white kidney bean extract) are mainly/possibly effective in diets rich in carbohydrates.
Please check out this abstract:
http://www.ncbi.nlm.nih.gov/pubmed/17658120
Some studies have found reasonably positive results:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796956/?tool=pubmed
The latest study isn’t very promising though - based on the typical dosage used:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776021/?tool=pubmed
More studies can be found via the manufacturer’s web site (all PDF files): http://www.phase2info.com/clinical-studies
Bottomline: I suspect that this variety of supplement wouldn’t be very useful … unless your diet is higher in carbs. If it is, I think it would be worth trying.
PS - I’m beginning to see a new variety of supplements containing sucrase inhibitors (such as L-arabinose) on the market. I’ve yet to see any clinical studies that support their use. Hopefully some evidence will come to light soon.
I hope this helps!
Be well!
JP
January 14th, 2010 at 10:51 pm
I purchase Jarrow Formulas’ Yaeyama Chlorella from iHerb. A 1 kilogram jar of powder costs less than $45.
January 14th, 2010 at 11:58 pm
Thanks for the tip, Hank.
That seems like a high quality product.
Be well!
JP
January 26th, 2010 at 1:54 am
I’m pregnant and I searched internet to find out if spirilina and chlorella are safe to take.So chlorella is but what about spirulina?Another sites says not but it old info 90’s.I would like to know about resent one…Thank you
January 26th, 2010 at 2:36 am
Anastasia,
I was only able to find animal studies re: spirulina and pregnancy:
“Spirulina appears to be effective in improving the iron status of rats during pregnancy and lactation.”
http://www.springerlink.com/content/n8117726156t658u/
“Treatment was not associated with any adverse effect on any measure of reproductive performance, including male and female fertility and duration of gestation. There was no increase in the number of abnormal pups at caesarean section or at birth. S. maxima consumption did not result in adverse effects on developmental markers of the pups.”
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T6P-3VXN1XX-4&_user=10&_coverDate=04%2F30%2F1996&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=54a6bc377769f269e319c439d24dfcb9
“Spirulina appears to be a good dietary supplement during pregnancy.”
http://www.ncbi.nlm.nih.gov/pubmed/8464842
“There is not enough information to recommend the safe use of spirulina during pregnancy or breastfeeding. In mice, diets containing up to 30% spirulina are not reported to cause harmful effects to either the mother or the offspring. However, reliable human studies addressing safety during pregnancy or breastfeeding are not available.”
http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-spirulina.html
Be well!
JP
March 5th, 2010 at 12:35 pm
Please tell me what brand has the best quality of chlorella. Thank you..
March 5th, 2010 at 3:50 pm
Silvia,
There are quite a few high quality brands currently available. Here are a few I’d personally consider:
Chlorenergy Chlorella
Sun Chlorella
Swanson Vitamins Kyoto Chlorella
Yaeyama Chlorella (contained in several brands such as Jarrow Formulas and Source Naturals)
I hope this helps!
Be well!
JP