Prescription 2019: Optimized Curcumin DosageJuly 9, 2019 Written by JP [Font too small?]
As a consumer, it’s not always clear how to best utilize a supplement for a specific objective. The challenges are many. For starters, you have to determine whether there’s reliable research available to guide you. If that exists, you’ll next need to determine whether the published evidence applies to your circumstance. Is it applicable to your age, gender, health-related status and weight? Then, there’s the question of determining the appropriate dosage. In many instances, even the manufacturers don’t know whether a higher or lower dose is more or less effective and safe than the doses used in the clinical studies. This leaves both the consumer and health care providers in a difficult spot that often requires educated guessing. However, in some instances there’s enough data in the scientific literature to provide a more accurate picture.
Longvida is a non-gmo, “optimized” form of curcumin that has been shown in peer-reviewed medical journals to provide functional and health benefits for the brain and body. It differs from most other turmeric-derived extracts in that it can cross the blood-brain barrier. Practically speaking, this means that Longvida has potential applications for a broad range of health concerns such as arthritis, diabetes, integrative cancer support and various forms of age-related cognitive decline.
One of the reasons why I often recommend Longvida is that it has a rather robust track record of yielding health benefits when tested in placebo-controlled trials. And, generally speaking, this applies to positive results relating to both the body and brain. Two recent examples from earlier this month report that Longvida supplementation effectively reduces knee osteoarthritis symptoms and improves mood and working memory in adults aged 50-80 years old. But, there is a bit of a confounding issue. The successful osteoarthritis study safely utilized 800 mg/day of this specialized supplement. The mood and neurocognitive function trial used half that dose or 400 mg/day. What’s more, prior research examining the effects of 2,000 mg/day Longvida on endothelial function and motor-cognitive function revealed mixed results – it enhanced artery function, but failed to improve brain performance.
In fact, the majority of positive results in the catalog of Longvida research involves once-daily supplementation of a 400 mg capsule – preferably taken without food. This same dosage has been therapeutically proven for other applications, such as reducing exercise-related muscle damage, which is another example of the aforementioned body benefits. Knowing all of this allows for interested parties to increase the likelihood of better results at a lower cost. Also, it is a valuable reminder that more isn’t always better.
Note: Please check out the “Comments & Updates” section of this blog – at the bottom of the page. You can find the latest research about this topic there!
To learn more about the studies referenced in today’s column, please click on the following links:
Study 1 – Longvida: Science and Selected References (link)
Study 2 – A Highly Bioavailable Curcumin Extract Improves Neurocognitive … (link)
Study 3 – Evaluation of the Efficacy and Safety of Longvida® Optimized Curcumin … (link)
Study 4 – Curcumin Supplementation and Motor-Cognitive Function in Healthy … (link)
Study 5 – Curcumin Supplementation Improves Vascular Endothelial Function … (link)
Study 6 – Investigation of the Effects of Solid Lipid Curcumin on Cognition & Mood … (link)
Study 7 – Reduced Inflammatory & Muscle Damage Biomarkers Following Oral … (link)
Study 8 – Diverse Effects of a Low Dose Supplement of Lipidated Curcumin in … (link)
Study 9 – Bioavailable Curcumin Formulations: A Review of Pharmacokinetic … (link)
Study 10 – Acute Human Pharmacokinetics of a Lipid-Dissolved Turmeric … (link)
Longvida Supplementation May Improve Mood & Vigor
Tags: Curcumin, Dementia, Inflammation
Posted in Alternative Therapies, Mental Health, Nutritional Supplements